Despite the marked improvement in the aortic dissection repair techniques, residual dissected aorta with a patent false lumen remains an issue. So, the aim of our study is to observe the effect of inserting the Thoraflex Hybrid Graft on the aortic diameters in patients with type A aortic dissection involving the arch and descending aorta. Patients with type I aortic dissection who had aortic dissection repair using the Thoraflex Hybrid Graft in University Hospitals Birmingham were studied. Radiological assessment with computed tomography of the aorta was done at the level of the diaphragm to measure the true lumen, false lumen and total aortic diameters. Significance of change of diameters at early post-operative as compared to the pre-operative period was analysed. Eight cases were done in the acute setting, while 14 cases were done in the chronic setting. The ratio of true lumen to the total aortic diameter has significantly increased in the follow-up period as compared to the pre-operative period (P = 0.031). Whereas false lumen to total aortic diameter ratio has significantly decreased (P = 0.024). Subgroup analysis revealed that these changes were not significantly altered by whether the dissection was acute or chronic. The Thoraflex Hybrid Graft will induce positive aortic remodelling with expansion of true lumen and will diminish the false lumen. But we could not find a significant difference between acute or chronic cases due to small sample size.

中文翻译：

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使用 thoraflex 混合支架移植物进行主动脉夹层冷冻象鼻技术后的主动脉重塑和假腔变化

尽管主动脉夹层修复技术有了显着改进，但带有明显假腔的残留主动脉夹层仍然是一个问题。因此，我们研究的目的是观察插入 Thoraflex Hybrid Graft 对涉及弓和降主动脉的 A 型主动脉夹层患者的主动脉直径的影响。研究了在伯明翰大学医院使用 Thoraflex Hybrid Graft 进行主动脉夹层修复的 I 型主动脉夹层患者。在横膈膜水平进行主动脉计算机断层扫描的放射学评估，以测量真腔、假腔和主动脉总直径。分析了术后早期与术前相比直径变化的意义。八例是在急性环境中完成的，而 14 例是在慢性环境中完成的。与术前相比，随访期间真腔与主动脉总直径之比显着增加（P = 0.031）。而假腔与主动脉总直径之比已显着降低（P = 0.024）。亚组分析显示，这些变化不会因夹层是急性还是慢性而显着改变。Thoraflex Hybrid Graft 将通过真腔扩张诱导主动脉重构，并减少假腔。但由于样本量小，我们无法发现急性或慢性病例之间的显着差异。而假腔与主动脉总直径之比已显着降低（P = 0.024）。亚组分析显示，这些变化不会因夹层是急性还是慢性而显着改变。Thoraflex Hybrid Graft 将通过真腔扩张诱导主动脉重构，并减少假腔。但由于样本量小，我们无法发现急性或慢性病例之间的显着差异。而假腔与主动脉总直径之比已显着降低（P = 0.024）。亚组分析显示，这些变化不会因夹层是急性还是慢性而显着改变。Thoraflex Hybrid Graft 将通过真腔扩张诱导主动脉重构，并减少假腔。但由于样本量小，我们无法发现急性或慢性病例之间的显着差异。