Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation
Circulation Research
(
IF20.1
)
Pub Date : 2021-08-26, DOI: 10.1161/circresaha.121.319425
Stephan R Künzel
1,
2
,
Maximilian Hoffmann
1
,
Silvio Weber
1
,
Karolina Künzel
1
,
Susanne Kämmerer
1
,
Mario Günscht
1
,
Erik Klapproth
1
,
Johanna S E Rausch
1
,
Mirna S Sadek
1
,
Tomasz Kolanowski
1
,
Stefanie Meyer-Roxlau
1
,
Christopher Piorkowski
3
,
Sems M Tugtekin
4
,
Stefan Rose-John
5
,
Xiaoke Yin
6
,
Manuel Mayr
6,
7
,
Jan Dominik Kuhlmann
8,
9,
10
,
Pauline Wimberger
8,
9,
10
,
Konrad Grützmann
1,
10
,
Natalie Herzog
11
,
Jan-Heiner Küpper
11
,
Molly O'Reilly
12
,
S Nashitha Kabir
12
,
Laura C Sommerfeld
12,
13
,
Kaomei Guan
,
Ben Wielockx
14
,
Larissa Fabritz
13,
15
,
Stanley Nattel
16,
17,
18
,
Ursula Ravens
19
,
Dobromir Dobrev
16,
17,
20
,
Michael Wagner
1,
3
,
Ali El-Armouche
1
Affiliation
Institute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden (S.R.K., M.H., S.W., K.K., S.K., M.G., E.K., J.S.E.R., M.S.S., T.K., S.M.-R., K.G., M.W., A.E.-A.).
Department of Dermatology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden (S.R.K.).
Department of Rhythmology (C.P., M.W.), Clinic for Internal Medicine and Cardiology, Heart Center Dresden GmbH, Dresden, Technische Universität Dresden.
Department of Cardiac Surgery (S.M.T.), Clinic for Internal Medicine and Cardiology, Heart Center Dresden GmbH, Dresden, Technische Universität Dresden.
Unit for Degradomics of the Protease Web, Institute of Biochemistry, University of Kiel (S.R.-J.).
The James Black Centre, King's College, University of London (X.Y., M.M.).
Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden (M.M.).
Department of Gynecology and Obstetrics, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden (J.D.K., P.W.).
German Cancer Consortium (DKTK), Dresden and German Cancer Research Center (DKFZ), Heidelberg (J.D.K., P.W.).
National Center for Tumor Diseases (NCT), Partner Site Dresden (J.D.K., P.W., K.G.).
Brandenburg University of Technology, Senftenberg (N.H., J.-H.K.).
Institute of Cardiovascular Sciences, University of Birmingham (M.O., S.N.K., L.C.S.).
University Center of Cardiovascular Science and Department of Cardiology, University Heart and Vascular Center Hamburg (L.F., L.C.S.).
Institute of Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden (B.W.).
Department of Cardiology, University Hospitals Birmingham (L.F.).
Department of Medicine, Montreal Heart Institute and Université de Montréal, Quebec, Canada (S.N., D.D.).
Institute of Pharmacology, West German Heart and Vascular Center, University Duisburg-Essen (S.N., D.D.).
IHU Liryc, Electrophysiology and Heart Modeling Institute, Fondation Bordeaux Université (S.N.).
Institut für Experimentelle Kardiovaskuläre Medizin, Universitäts Herzzentrum, Freiburg Bad Krotzingen, Freiburg im Breisgau (U.R.).
Department of Molecular Physiology and Biophysics, Baylor College of Medicine (D.D.).
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