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Radio frequency plasma assisted surface modification of Fe3O4 nanoparticles using polyaniline/polypyrrole for bioimaging and magnetic hyperthermia applications
Journal of Materials Science: Materials in Medicine ( IF 3.7 ) Pub Date : 2021-08-25 , DOI: 10.1007/s10856-021-06563-1
Beena Mol 1 , Ansar Ereath Beeran 2, 3 , Prasad S Jayaram 4 , Prabha Prakash 5, 6 , Ramapurath S Jayasree 4 , Senoy Thomas 1 , Baby Chakrapani 5, 6 , M R Anantharaman 1 , M Junaid Bushiri 1
Affiliation  

Surface modification of superparamagnetic Fe3O4 nanoparticles using polymers (polyaniline/polypyrrole) was done by radio frequency (r.f.) plasma polymerization technique and characterized by XRD, TEM, TG/DTA and VSM. Surface-passivated Fe3O4 nanoparticles with polymers were having spherical/rod-shaped structures with superparamagnetic properties. Broad visible photoluminescence emission bands were observed at 445 and 580 nm for polyaniline-coated Fe3O4 and at 488 nm for polypyrrole-coated Fe3O4. These samples exhibit good fluorescence emissions with L929 cellular assay and were non-toxic. Magnetic hyperthermia response of Fe3O4 and polymer (polyaniline/polypyrrole)-coated Fe3O4 was evaluated and all the samples exhibit hyperthermia activity in the range of 42–45 °C. Specific loss power (SLP) values of polyaniline and polypyrrole-coated Fe3O4 nanoparticles (5 and 10 mg/ml) exhibit a controlled heat generation with an increase in the magnetic field.



中文翻译:

使用聚苯胺/聚吡咯对 Fe3O4 纳米粒子进行射频等离子体辅助表面改性,用于生物成像和磁热疗应用

使用聚合物(聚苯胺/聚吡咯)对超顺磁性Fe 3 O 4纳米粒子进行表面改性是通过射频(rf)等离子体聚合技术进行的,并通过XRD、TEM、TG/DTA和VSM进行表征。具有聚合物的表面钝化的Fe 3 O 4纳米颗粒具有具有超顺磁性的球形/棒状结构。对于涂有聚苯胺的 Fe 3 O 4 在 445 和 580 nm 处观察到宽的可见光致发光发射带,对于涂有聚吡咯的 Fe 3 O 4则在 488 nm观察。这些样品在 L929 细胞分析中表现出良好的荧光发射,并且无毒。Fe的磁热疗反应对3 O 4和聚合物(聚苯胺/聚吡咯)包覆的 Fe 3 O 4进行了评估,所有样品在 42-45 °C 范围内都表现出热疗活性。聚苯胺和聚吡咯涂层的 Fe 3 O 4纳米颗粒(5 和 10 mg/ml)的比损耗功率 (SLP) 值随着磁场的增加表现出受控的发热。

更新日期:2021-08-26
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