Non-aureus staphylococci (NAS) and Staphylococcus aureus are pathogens that cause bovine mastitis, a costly disease for dairy farmers, however; many NAS are considered part of the normal udder microbiota. It has been suggested that through a mechanism that remains to be elucidated, NAS intramammary colonization can prevent subsequent infection with other bacterial pathogens. This study shows that in a murine mastitis model, secondary Staph. aureus intramammary colonization is reduced by exoproducts from Staph. chromogenes and Staph. simulans, both NAS, while Streptococcus spp. exoproducts have much less ability to affect the course of the infection caused by S. aureus.

然而，非金黄色葡萄球菌(NAS) 和金黄色葡萄球菌是引起牛乳腺炎的病原体，这对奶农来说是一种代价高昂的疾病；许多 NAS 被认为是正常乳房微生物群的一部分。有人提出，通过一种仍有待阐明的机制，NAS 乳腺内定植可以防止随后感染其他细菌病原体。这项研究表明，在鼠乳腺炎模型中，继发性葡萄球菌。金黄色葡萄球菌的乳房内定植因葡萄球菌的外产物而减少。色原体和葡萄球菌。simulans，均为 NAS，而Streptococcus spp。外产物对金黄色葡萄球菌感染过程的影响要小得多.