In the present work, the extensive biological activities of marine endophytic Streptomyces strains isolated from marine soft coral Sarcophyton convolutum have been demonstrated. Within fifty-one Streptomyces isolates evaluated for their hydrolytic enzymes and enzyme inhibitors productivities, six isolates showed the hyperactivities. Pharmaceutical metabolites productivities evaluated include enzymes (alkaline protease, L-asparaginase, L-glutaminase, tyrosinase, and L-methioninase) and enzyme inhibitors (inhibitors of α-amylase, hyaluronidase, β-lactamase, α-glucosidase, and β-glucosidase). These isolates were identified based on their morphological, biochemical, and genetic characteristics as Streptomyces sp. MORSY 17, Streptomyces sp. MORSY 22, Streptomyces sp. MORSY 25, Streptomyces sp. MORSY 36, Streptomyces sp. MORSY 45, and Streptomyces sp. MORSY 50. Moreover, in further evaluation, these strains exhibited wide spectrum of antimicrobial (against bacteria and fungi), antiviral (against hepatitis C virus), antibiofilm against biofilm-forming bacteria (methicillin-resistant Staphylococcus aureus and multidrug-resistant Pseudomonas species), and anti-proliferative activities (against liver and colon carcinoma cell lines). The GC–MS analysis of the hyperactive strains MORSY 17 and MORSY 22 revealed the presence of different bioactive agents in the ethyl acetate extract of both strains.

在目前的工作中，已经证明了从海洋软珊瑚Sarcophyton convolutum 中分离出的海洋内生链霉菌菌株的广泛生物活性。在评估其水解酶和酶抑制剂生产力的51 个链霉菌分离株中，6 个分离株表现出过度活跃。评估的药物代谢产物生产力包括酶（碱性蛋白酶、L-天冬酰胺酶、L-谷氨酰胺酶、酪氨酸酶和 L-蛋氨酸酶）和酶抑制剂（α-淀粉酶、透明质酸酶、β-内酰胺酶、α-葡萄糖苷酶和β-葡萄糖苷酶的抑制剂） . 这些分离株根据其形态、生化和遗传特征被鉴定为链霉菌属。莫西 17,链霉菌属 MORSY 22，链霉菌属。MORSY 25，链霉菌属。MORSY 36，链霉菌属。MORSY 45 和链霉菌属。MORSY 50. 此外，在进一步评估中，这些菌株表现出广谱的抗菌（针对细菌和真菌）、抗病毒（针对丙型肝炎病毒）、针对生物膜形成细菌（耐甲氧西林金黄色葡萄球菌和耐多药假单胞菌）的抗生物膜种）和抗增殖活性（针对肝脏和结肠癌细胞系）。高活性菌株 MORSY 17 和 MORSY 22 的 GC-MS 分析表明，两种菌株的乙酸乙酯提取物中都存在不同的生物活性剂。