当前位置:
X-MOL 学术
›
Clin. Transl. Immunol.
›
论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Epigenetic programming underpins B-cell dysfunction in peanut and multi-food allergy
Clinical & Translational Immunology ( IF 5.8 ) Pub Date : 2021-08-24 , DOI: 10.1002/cti2.1324 Samira Imran 1 , Melanie R Neeland 1 , Jennifer Koplin 1 , Shyamali Dharmage 1, 2 , Mimi Lk Tang 1, 3 , Susan Sawyer 1, 4 , Thanh Dang 1 , Vicki McWilliam 1, 3 , Rachel Peters 1 , Kirsten P Perrett 1, 3 , Boris Novakovic 1 , Richard Saffery 1
Clinical & Translational Immunology ( IF 5.8 ) Pub Date : 2021-08-24 , DOI: 10.1002/cti2.1324 Samira Imran 1 , Melanie R Neeland 1 , Jennifer Koplin 1 , Shyamali Dharmage 1, 2 , Mimi Lk Tang 1, 3 , Susan Sawyer 1, 4 , Thanh Dang 1 , Vicki McWilliam 1, 3 , Rachel Peters 1 , Kirsten P Perrett 1, 3 , Boris Novakovic 1 , Richard Saffery 1
Affiliation
Rates of IgE-mediated food allergy (FA) have increased over the last few decades, and mounting evidence implicates disruption of epigenetic profiles in various immune cell types in FA development. Recent data implicate B-cell dysfunction in FA; however, few studies have examined epigenetic changes within these cells.
中文翻译:
表观遗传编程支持花生和多种食物过敏的 B 细胞功能障碍
在过去的几十年中,IgE 介导的食物过敏 (FA) 的发生率有所增加,越来越多的证据表明,FA 发育过程中各种免疫细胞类型的表观遗传谱被破坏。最近的数据表明 FA 中的 B 细胞功能障碍;然而,很少有研究检查这些细胞内的表观遗传变化。
更新日期:2021-08-25
中文翻译:
表观遗传编程支持花生和多种食物过敏的 B 细胞功能障碍
在过去的几十年中,IgE 介导的食物过敏 (FA) 的发生率有所增加,越来越多的证据表明,FA 发育过程中各种免疫细胞类型的表观遗传谱被破坏。最近的数据表明 FA 中的 B 细胞功能障碍;然而,很少有研究检查这些细胞内的表观遗传变化。