INTRODUCTION Skin is the largest organ of the human body protecting the underlying organs and tissues from any foreign attack. Any damage caused in the skin may sometimes result in serious consequences within the internal body tissues. Burn is one such issue that damages the layers of the skin and thereby making the skin vulnerable and prone to any foreign matter entering and causing serious diseases. METHODS An online literature assessment was steered for the lipid nanoparticles, burn wound treatments, and different types of nanoformulation. Appropriate information was taken from different electronic scientific databases such as Web of Science, Elsevier, Science Direct, Springer, PubMed, Google Scholar etc. Additional data was summarized from textbooks, local prints and scripts. RESULTS Recent innovations and developments in nanotechnology-based drug delivery systems have shown promising results in minimizing the drawbacks associated with conventional therapies. Lipid based nanoparticles possess capabilities to deliver active agents to their target site without the possibility of degradation. Conventional therapy of burn wound is costly and the treatment is long lasting, making the patient uncomfortable. Moreover, it also doesn't yield satisfactory results or narrow effects. Encapsulation of bioactives inside the lipid core protects the active entity from pH and enzymatic degradations. CONCLUSION This review highlights the drawbacks associated with conventional dosage forms. A lot of consideration is focused on the advancement of nanomaterials using innovative methods in wound care for treating burn wounds with a faster healing effect. This review article highlights recent developments in lipid based nanoformulations for the treatment of burn wound injury.

中文翻译：

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用于烧伤治疗的脂质工程纳米粒子疗法。

引言 皮肤是人体最大的器官，保护下面的器官和组织免受任何外来攻击。对皮肤造成的任何损伤有时可能会在身体内部组织内造成严重后果。烧伤就是这样一个问题，它会破坏皮肤的各个层，从而使皮肤变得脆弱，容易受到任何异物的影响，从而导致严重的疾病。方法 对脂质纳米颗粒、烧伤伤口治疗和不同类型的纳米制剂进行在线文献评估。适当的信息取自不同的电子科学数据库，如 Web of Science、Elsevier、Science Direct、Springer、PubMed、Google Scholar 等。其他数据来自教科书、本地印刷品和脚本。结果 基于纳米技术的药物输送系统的最新创新和发展在最大限度地减少与传统疗法相关的缺点方面显示出有希望的结果。基于脂质的纳米粒子具有将活性剂递送至其靶位点而不可能降解的能力。烧伤创面常规治疗费用高，治疗时间长，患者不舒服。而且，它也没有产生令人满意的结果或狭窄的效果。将生物活性物质包裹在脂质核心内可保护活性实体免受 pH 和酶促降解。结论 本综述强调了与传统剂型相关的缺点。很多考虑都集中在纳米材料的进步上，在伤口护理中使用创新方法来治疗具有更快愈合效果的烧伤伤口。这篇综述文章重点介绍了用于治疗烧伤损伤的脂质纳米制剂的最新进展。