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Bone mineral density in progestogen-only implant and pill users with amenorrhoea: a pilot study
BMJ Sexual & Reproductive Health ( IF 3.3 ) Pub Date : 2021-08-24 , DOI: 10.1136/bmjsrh-2021-201184
Rebecca L Heller 1 , Sharon Cameron 2, 3 , Anne Johnstone 3 , Rosemary Cochrane 2 , Anna Glasier 3
Affiliation  

Although there is good evidence that the progestogen-only injectable is associated with a decrease in bone mineral density (BMD), there is a lack of data pertaining to lower dose progestogen-only methods.1 2 The recent guidance from the Clinical Effectiveness Unit of the Faculty of Sexual and Reproductive Healthcare advises that current evidence is too limited to confirm or exclude an association between implant use and a reduction in BMD.3 Amenorrhoea results from suppression of ovarian follicle growth and of oestrogen secretion.4 It is therefore possible that amenorrhoeic women using any systemic progestogen-only contraception that suppresses ovarian activity may be more at …

中文翻译:

仅使用孕激素的植入物和药丸使用者闭经的骨矿物质密度:一项初步研究

尽管有充分的证据表明仅使用孕激素的注射剂与骨矿物质密度 (BMD) 降低有关,但缺乏与低剂量仅使用孕激素的方法相关的数据。 1 2性与生殖保健学院建议,目前的证据太有限,无法证实或排除植入物使用与 BMD 降低之间的关联。 3 闭经是由抑制卵巢卵泡生长和雌激素分泌引起的。 4 因此,闭经可能使用任何抑制卵巢活动的全身性纯孕激素避孕药的女性可能更...
更新日期:2021-08-24
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