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The early interferon catches the SARS-CoV-2
Journal of Experimental Medicine ( IF 15.3 ) Pub Date : 2021-08-23 , DOI: 10.1084/jem.20211667
Thomas Decker 1
Affiliation  

Interferons establish innate antiviral immunity. Two recent papers in JEM by Lopez et al. (2021. J. Exp. Med.https://doi.org/10.1084/jem.20211211) and Cheemarla et al. (2021. J. Exp. Med.https://doi.org/10.1084/jem.20210583) show that an appropriate supply of antiviral interferon enables epithelial cells of the nasopharyngeal mucosa to inhibit SARS-CoV-2 growth and that interferon-induced mucosal genes serve as biomarkers of infection.

中文翻译:

早期干扰素捕获 SARS-CoV-2

干扰素建立先天抗病毒免疫。Lopez 等人最近在JEM 上发表的两篇论文。(2021. J. Exp. Med. https://doi.org/10.1084/jem.20211211) 和 Cheemarla 等人。(2021. J. Exp. Med. https://doi.org/10.1084/jem.20210583) 表明,适当供应抗病毒干扰素可使鼻咽粘膜上皮细胞抑制 SARS-CoV-2 的生长,并且干扰素-诱导的粘膜基因作为感染的生物标志物。
更新日期:2021-08-24
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