This paper reviews the application of ambient desorption/ionization (ADI) mass spectrometry (MS) to the direct analysis of solid materials. First, ADI methods are introduced according to the sampling and desorption processes, including liquid extraction, plasma desorption, thermal desorption, and laser ablation/desorption, along with their practical features and limitations in the direct analysis of solid objects. Various cases of real-world analysis are also summarized: analysis of active compounds in pharmaceuticals and herbal medicines; analysis of food products for quality control and origin tracking; forensic analysis for sexual assault crimes, explosives, and illicit drug abuse; and surface contaminant analysis for food and environmental safety control. An overview of relevant discussions shows that ADI-MS techniques allow the direct desorption and ionization of analytes from untreated samples under ambient conditions, resulting in tremendous improvements in efficiency in speed and procedural simplicity.

本文回顾了常温解吸/电离 (ADI) 质谱 (MS) 在固体材料直接分析中的应用。首先，根据采样和解吸过程，包括液体提取、等离子体解吸、热解吸和激光烧蚀/解吸，以及它们在固体物体直接分析中的实际特点和局限性，介绍了 ADI 方法。还总结了现实世界分析的各种案例：药物和草药中活性化合物的分析；食品质量控制和原产地跟踪分析；性侵犯犯罪、爆炸物和非法药物滥用的法医分析；用于食品和环境安全控制的表面污染物分析。