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Restoring control over autoimmunity by inducing Foxp3
Nature Immunology ( IF 30.5 ) Pub Date : 2021-08-23 , DOI: 10.1038/s41590-021-01008-x
Masahiro Ono 1
Affiliation  

Autoimmune inflammation and disease creates an environment that results in defective regulatory T (Treg) cell functions. New data show how induction of Foxp3 expression in these Treg cells during ongoing autoimmune inflammation can restore control over pathogenic T cell functions and resolve inflammation and pathology in mice.

中文翻译:

通过诱导 Foxp3 恢复对自身免疫的控制

自身免疫性炎症和疾病会产生导致调节性 T (Treg) 细胞功能缺陷的环境。新数据显示,在持续的自身免疫性炎症期间,在这些 Treg 细胞中诱导 Foxp3 表达如何可以恢复对致病性 T 细胞功能的控制并解决小鼠的炎症和病理。
更新日期:2021-08-23
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