Titanium is an attractive metal for catalytic reaction development: it is earth-abundant, inexpensive, and generally nontoxic. However—like most early transition metals—catalytic redox reactions with Ti are difficult because of the stability of the high-valent Ti^IV state. Understanding the fundamental mechanisms behind Ti redox processes is key for making progress toward potential catalytic applications. This Account details recent progress in Ti-catalyzed (and -mediated) oxidative amination reactions that proceed through formally Ti^II/Ti^IV catalytic cycles.

中文翻译：

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钛催化和介导的氧化胺化反应

钛是用于催化反应发展的有吸引力的金属：它富含地球、廉价且通常无毒。然而，与大多数早期过渡金属一样，由于高价 Ti ^IV态的稳定性，与 Ti 的催化氧化还原反应很困难。了解钛氧化还原过程背后的基本机制是在潜在催化应用方面取得进展的关键。^{该帐户详细介绍了通过正式的 Ti II} /Ti ^IV催化循环进行的 Ti 催化（和介导的）氧化胺化反应的最新进展。