Gait Variability in Spinocerebellar Ataxia Assessed Using Wearable Inertial Sensors,Movement Disorders

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Gait Variability in Spinocerebellar Ataxia Assessed Using Wearable Inertial Sensors
Movement Disorders ( IF 8.6 ) Pub Date : 2021-08-23 , DOI: 10.1002/mds.28740
Vrutangkumar V Shah ₁ , Roberto Rodriguez-Labrada _{2,

3} , Fay B Horak _{1,

4} , James McNames _{4,

5} , Hannah Casey ₆ , Kyra Hansson Floyd ₆ , Mahmoud El-Gohary ₄ , Jeremy D Schmahmann ₇ , Liana S Rosenthal ₈ , Susan Perlman ₉ , Luis Velázquez-Pérez _{2,

10} , Christopher M Gomez _{1,

6}

Affiliation

Department of Neurology, Oregon Health & Science University, Portland, Oregon, USA.
Centre for the Research and Rehabilitation of Hereditary Ataxias, Holguín, Cuba.
Cuban Center for Neuroscience, Havana, Cuba.
APDM Wearable Technologies, an ERT company, Portland, Oregon, USA.
Department of Electrical and Computer Engineering, Portland State University, Portland, Oregon, USA.
The University of Chicago, Chicago, Illinois, USA.
Department of Neurology, Ataxia Center, Laboratory for Neuroanatomy and Cerebellar Neurobiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Department of Neurology, University of California, Los Angeles, California, USA.
Cuban Academy of Sciences, La Habana, Cuba.

Quantitative assessment of severity of ataxia-specific gait impairments from wearable technology could provide sensitive performance outcome measures with high face validity to power clinical trials.

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