Aims

To describe burden and health-related quality of life amongst caregivers of out-of-hospital cardiac arrest survivors and explore the potential association with cognitive function of the survivors. Caregivers of patients with ST-elevation myocardial infarction were used as controls.

Methods

Data were collected from the cognitive substudy of the Targeted Temperature Management-trial. Caregiver burden was assessed with the 22-item Zarit Burden Interview, with scores ≤20 considered as no burden. Health-related quality of life was assessed with the SF-36v2®, with T-scores 47–53 representing the norm. Cardiac arrest survivors were categorized based on the results from cognitive assessments as having “no cognitive impairment” or “cognitive impairment”.

Results

Follow-up 6 months post event was performed for caregivers of 272 cardiac arrest survivors and 108 matched myocardial infarction controls, included at an intended ratio of 2:1. In general, caregivers of cardiac arrest survivors and controls reported similar caregiver burden. The overall scores for quality of life were within normative levels and similar for caregivers of cardiac arrest survivors and control patients. Compared to those with no cognitive impairment, caregivers of cognitively impaired cardiac arrest survivors (n = 126) reported higher levels of burden (median 18 versus 8, p < 0.001) and worse quality of life in five of eight domains, particularly “Role-Emotional” (mean 45.7 versus 49.5, p = 0.002).

Conclusions

In general, caregivers of cardiac arrest survivors and myocardial infarction controls reported similar levels of burden and quality of life. Cognitive outcome and functional dependency of the cardiac arrest survivor impact burden and quality of life of the caregiver.

中文翻译：

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院外心脏骤停幸存者的照顾者的照顾者负担和健康相关的生活质量

宗旨

描述院外心脏骤停幸存者的照顾者的负担和健康相关的生活质量，并探索与幸存者认知功能的潜在关联。ST 段抬高型心肌梗死患者的照顾者作为对照。

方法

数据来自目标温度管理试验的认知子研究。照顾者的负担通过 22 项 Zarit Burden 访谈进行评估，得分≤20 被视为无负担。使用 SF-36v2® 评估与健康相关的生活质量，T 分数 47-53 代表标准。心脏骤停幸存者根据认知评估结果分为“无认知障碍”或“认知障碍”。

结果

对 272 名心脏骤停幸存者和 108 名匹配的心肌梗死对照者的护理人员进行了事件后 6 个月的随访，预期比例为 2:1。一般而言，心脏骤停幸存者和对照组的护理人员报告了类似的护理人员负担。心脏骤停幸存者和对照患者的护理人员的生活质量总体评分在规范水平内并且相似。与没有认知障碍的人相比，有认知障碍的心脏骤停幸存者 ( n  = 126) 的照顾者报告称， 在八个领域中的五个领域中，负担水平更高（中位数为 18 对 8，p < 0.001）和更差的生活质量，尤其是“角色”情绪”（平均 45.7 对 49.5，p  = 0.002）。

结论

一般而言，心脏骤停幸存者和心肌梗死对照者的护理人员报告的负担水平和生活质量相似。心脏骤停幸存者的认知结果和功能依赖性影响照顾者的负担和生活质量。