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Localized eruptive porokeratosis in pediatric patients following treatment of acute leukemia
Pediatric Dermatology ( IF 1.5 ) Pub Date : 2021-08-21 , DOI: 10.1111/pde.14772
Bianca Y Kang 1 , Jeffrey Jacobsen 2 , Harper N Price 3 , Israel D Andrews 3
Affiliation  

Porokeratosis is a rare diagnosis in the pediatric population, and eruptive disease has been documented prior in patients with history of stem cell transplantation. Comparing various porokeratosis eruptions between patients can be difficult due to limitations in current classification and nomenclature. Here, we discuss a single-institution case series of three children who developed porokeratosis following hematopoietic stem cell transplantation for acute leukemia, and we propose that this presentation be termed localized eruptive porokeratosis (LEP). We present the distinguishing features of this variant by discussing the shortcomings in current nomenclature and also examine the association between porokeratosis and hematopoietic stem cell transplantation in the pediatric population.

中文翻译:

儿童急性白血病治疗后局部发疹性汗孔角化症

汗孔角化病在儿科人群中是一种罕见的诊断,并且在有干细胞移植史的患者之前已经记录了发疹性疾病。由于当前分类和命名法的限制,比较患者之间的各种汗孔角化病爆发可能很困难。在这里,我们讨论了一个单一机构的病例系列,这些儿童在急性白血病的造血干细胞移植后出现了汗孔角化病,我们建议将这种表现称为局部发疹性汗孔角化病 (LEP)。我们通过讨论当前命名法的缺点来展示该变体的显着特征,并检查儿科人群中汗孔角化症与造血干细胞移植之间的关联。
更新日期:2021-08-21
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