Compared with many chemotherapy and radiotherapy modalities, selective killing of cancer cells is a pivotal feature of cold atmospheric plasma (CAP). Understanding its underlying mechanism will build the foundation of CAP-based cancer treatment. Additionally, we provided forward-looking thinking to extend the definition of selectivity from conventional cases involving a single-cell line to a coculture case. Finally, the newly established physically based treatment strategy provides unprecedented visions to realize selectivity beyond the previously established concepts based on reactive species and direct killing effect.

中文翻译：

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关于选择性杀死冷大气等离子体癌症治疗：现状及以后

与许多化疗和放疗方式相比，选择性杀死癌细胞是冷大气等离子体 (CAP) 的一个关键特征。了解其潜在机制将为基于 CAP 的癌症治疗奠定基础。此外，我们提供了前瞻性思维，将选择性的定义从涉及单细胞系的传统案例扩展到共培养案例。最后，新建立的基于物理的处理策略提供了前所未有的愿景，以实现超越先前建立的基于反应物种和直接杀伤效应概念的选择性。