This paper reports on the in vitro assessment of the acid resistance characteristics of mesoporous silica/nanohydroxyapatite (MSN@nHAp) biocomposite synthesized through the mechanochemical method. Bovine enamel models were used to study the acid resistance characteristics of the composite (). X-ray diffraction and Fourier transform infrared spectroscopy were used to characterize the surface morphology of the MSN@nHAp. The XRD and FTIR results confirmed the successful syntheses and surface modification of nanohydroxyapatite with silica. The MSN@nHAp exhibits superior acid resistance characteristics. The salient aspect of this study suggests that mechanochemistry is a useful technique in the synthesis and surface modification of valuable biomaterials. The study concludes that the MSN@nHAp composite could be utilised in toothpaste formulation for oral healthcare management due to its acid resistance properties.

中文翻译：

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使用机械化学合成的纳米羟基磷灰石/二氧化硅生物复合材料的耐酸性特性的体外评估

本文报道了通过机械化学方法合成的介孔二氧化硅/纳米羟基磷灰石 (MSN@nHAp) 生物复合材料的耐酸性特性的体外评估。采用牛搪瓷模型研究复合材料的耐酸特性（）。X射线衍射和傅里叶变换红外光谱用于表征MSN@nHAp的表面形貌。XRD 和 FTIR 结果证实了纳米羟基磷灰石与二氧化硅的成功合成和表面改性。MSN@nHAp 表现出优异的耐酸性特性。这项研究的突出方面表明，机械化学是一种有用的技术，可用于合成和表面改性有价值的生物材料。该研究得出的结论是，MSN@nHAp 复合材料由于其耐酸性特性，可用于口腔保健管理的牙膏配方。