Objective To investigate the diagnostic value of three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) MRI in children with sudden deafness caused by inner ear hemorrhage. Methods The diagnostic efficacies of three different MRI sequences in the examination of the inner ear for 32 children with sudden deafness were compared. Hearing examination results and 3-month follow-up outcomes were analyzed. Results The age of 32 children with sudden deafness ranged from 5 to 18 years. MRI was performed from 1 to 18 days after onset. Six cases of sudden deafness caused by inner ear hemorrhage were finally diagnosed clinically. For different MRI sequences, the 3D-FLAIR sequence detected five positive cases; the conventional T1-weighted image sequence also detected five positive cases; but the conventional T2-weighted image sequence only detected three positive cases. The sensitivity and specificity of the 3D-FLAIR sequence in the diagnosis of inner ear hemorrhage were 83.3% (5/6) and 96.2% (25/26), respectively, and the area under the curve value of the receiver operating characteristic curve was 0.897. In the hemorrhage group, all six cases had extremely severe sensorineural hearing loss, and the hearing recovery was ineffective after 3 months of follow-up. The degree of hearing impairment, 3-month short-term treatment efficacy, and 3D-FLAIR MRI in the diagnosis of inner ear hemorrhage between hemorrhage group and non-hemorrhage group were statistically significant (p=0.043, p=0.000, p=0.000). Conclusions 3D-FLAIR MRI is helpful for the diagnosis of inner ear hemorrhage in children with sudden deafness. Besides, short-term treatment indicates poor effects on children with severe hearing impairment. All data relevant to the study are included in the article or uploaded as supplemental information.

中文翻译：

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3D-FLAIR MRI对小儿内耳出血所致突发性耳聋的诊断价值

目的探讨三维流体衰减反转恢复（3D-FLAIR）MRI对内耳出血致突发性耳聋患儿的诊断价值。方法比较三种不同MRI序列对32例突发性耳聋患儿内耳检查的诊断效果。分析了听力检查结果和 3 个月的随访结果。结果突发性耳聋患儿32例，年龄5～18岁。发病后 1 至 18 天进行 MRI。6例内耳出血引起的突发性耳聋经临床最终确诊。对于不同的 MRI 序列，3D-FLAIR 序列检测到 5 个阳性病例；传统的 T1 加权图像序列也检测到 5 个阳性病例；但传统的 T2 加权图像序列仅检测到三个阳性病例。3D-FLAIR序列诊断内耳出血的敏感性和特异性分别为83.3%（5/6）和96.2%（25/26），受试者工作特征曲线曲线下面积为0.897。出血组6例均出现极重度感音神经性耳聋，随访3个月听力恢复无效。出血组与非出血组的听力损伤程度、3个月短期治疗效果、3D-FLAIR MRI诊断内耳出血的差异均有统计学意义（p=0.043，p=0.000，p=0.000） ). 结论 3D-FLAIR MRI有助于突发性耳聋患儿内耳出血的诊断。除了，短期治疗表明对严重听力障碍的儿童效果不佳。与研究相关的所有数据都包含在文章中或作为补充信息上传。