Urinary albumin creatinine ratio associated with postoperative delirium in elderly patients undergoing elective non-cardiac surgery: A prospective observational study,CNS Neuroscience & Therapeutics

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Urinary albumin creatinine ratio associated with postoperative delirium in elderly patients undergoing elective non-cardiac surgery: A prospective observational study
CNS Neuroscience & Therapeutics ( IF 5.5 ) Pub Date : 2021-08-20 , DOI: 10.1111/cns.13717
Hui-Lian Guan _{1,

2,

3} , He Liu ₄ , Xiao-Yi Hu _{1,

2} , Mannan Abdul _{1,

2} , Ming-Sheng Dai _{1,

2} , Xing Gao _{1,

2} , Xue-Fen Chen ₅ , Yang Zhou _{1,

2} , Xun Sun _{1,

2} , Jian Zhou _{1,

2} , Xiang Li _{1,

2} , Qiu Zhao _{1,

2} , Qian-Qian Zhang _{1,

2} , Jun Wang _{1,

2} , Yuan Han ₆ , Jun-Li Cao _{1,

2}

Affiliation

The blood-brain barrier (BBB) disruption contributes to postoperative delirium, but cost-effective and non-invasive assessment of its permeability is not practicable in the clinical settings. Urine albumin to creatinine ratio (UACR), reflecting systemic vascular endothelial dysfunction, may be a prognostic and predictive factor associated with postoperative delirium. The aim was to analyze the relationship between UACR and postoperative delirium in elderly patients undergoing elective non-cardiac surgery.

中文翻译：

老年择期非心脏手术患者尿白蛋白肌酐比值与术后谵妄的相关性：一项前瞻性观察研究

血脑屏障 (BBB) 破坏会导致术后谵妄，但在临床环境中对其通透性进行成本效益和非侵入性评估是不切实际的。反映全身血管内皮功能障碍的尿白蛋白与肌酐比值 (UACR) 可能是与术后谵妄相关的预后和预测因素。目的是分析UACR与老年择期非心脏手术患者术后谵妄之间的关系。

更新日期：2021-08-20

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