Hepatosplenic lymphoma (HSTCL) is a rare T-cell malignancy occurring in young males, associated with immune deficiency in 20% of the cases which, despite aggressive treatments, has a poor survival. Specific recommendations for first-line treatment remain debatable.

中文翻译：

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肝脾 T 细胞淋巴瘤：治疗挑战。

肝脾淋巴瘤 (HSTCL) 是一种罕见的 T 细胞恶性肿瘤，发生于年轻男性，20% 的病例与免疫缺陷有关，尽管经过积极治疗，其生存率仍很差。一线治疗的具体建议仍有争议。