Dose distrubution evaluation of different dental implants on a real human dry-skull model for head and neck cancer radiotherapy,Radiation Physics and Chemistry

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Dose distrubution evaluation of different dental implants on a real human dry-skull model for head and neck cancer radiotherapy
Radiation Physics and Chemistry ( IF 2.9 ) Pub Date : 2021-08-20 , DOI: 10.1016/j.radphyschem.2021.109751
Oya Akyol ₁ , Turan Olgar ₂ , Turkay Toklu ₃ , Hakan Eren ₄ , Bahar Dirican ₅

Affiliation

Objectives

In this study, the effect of different dental implant materials on dose distribution in head and neck cancer radiotherapy planning was investigated in a real human dry-skull taken from cadaver.

Methods

The effect of Root-shaped Yttrium (Y) stabilized tetragonal Zr polycrystalline (Y-TZP), Titanium (Ti), Alumina (Al₂O₃) and polyether ether ketone (PEEK) dental implants on dose distribution was investigated by three different methods; Monte Carlo (MC) simulation, Eclipse Treatment Planning System's (TPS) Pencil Beam Convolution (PBC) algorithm and Thermoluminescence Dosimeter (TLD). The 6 MV photon beam simulation was performed for the Varian 2300 C/D linear accelerator using the EGSnrc based BEAMnrc MC Code. To perform MC simulation on skull phantom, phantom CT images with extended CT scale were imported to BEAMnrc/EGSnrc MC code via CTCREATE code.

Results

According to the dose distribution measurement in dry skull, the calculated dose differences between PBC and MC algorithms were in the range of 0.6–4.5% whereas the dose difference between MC and TLD were in the range of 1,1–14.6% range depending on implant material. The PBC calculated dose increase difference range confirmed with TLD measurements was between 1.7% and 19.8%. The PBC algorithm could not fully determine the dose due to backscattering caused by dental implants. This is probably due to the limitations and shortcomings of the PBC algorithm.

Conclusion

The maximum dose increase was observed for the Y-TZP dental implant material, which has the highest physical density. No significant dose increase was observed for the PEEK implant probably due to the low physical density of implants close to the physical density of water.

中文翻译：

头颈癌放疗真人干颅模型上不同牙种植体的剂量分布评价

目标

在这项研究中，在取自尸体的真实人类干颅骨中研究了不同牙种植体材料对头颈部癌症放射治疗计划中剂量分布的影响。

方法

通过三种不同的方法研究了根形钇 (Y) 稳定四方 Zr 多晶 (Y-TZP)、钛 (Ti)、氧化铝 (Al ₂ O ₃ ) 和聚醚醚酮 (PEEK) 牙种植体对剂量分布的影响; 蒙特卡罗 (MC) 模拟、Eclipse 治疗计划系统 (TPS) 的铅笔束卷积 (PBC) 算法和热释光剂量计 (TLD)。使用基于 EGSnrc 的 BEAMnrc MC 代码对 Varian 2300 C/D 直线加速器执行 6 MV 光子束模拟。为了对颅骨模型进行 MC 模拟，通过 CTCREATE 代码将具有扩展 CT 比例的模型 CT 图像导入到 BEAMnrc/EGSnrc MC 代码中。

结果

根据干颅骨中的剂量分布测量，计算出的 PBC 和 MC 算法之间的剂量差异在 0.6-4.5% 范围内，而 MC 和 TLD 之间的剂量差异在 1.1-14.6% 范围内，具体取决于植入材料。经 TLD 测量证实的 PBC 计算的剂量增加差异范围介于 1.7% 和 19.8% 之间。由于牙种植体引起的反向散射，PBC 算法无法完全确定剂量。这可能是由于 PBC 算法的局限性和缺点。