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Interaction of Catecholamines with Microorganisms, Neurons, and Immune Cells
Biology Bulletin Reviews Pub Date : 2021-08-16 , DOI: 10.1134/s2079086421040058
A. V. Oleskin 1 , E. V. Sorokina 1 , G. A. Shilovsky 1, 2
Affiliation  

Abstract

The review presents current data on cellular communication in the binary host–microbiota system. Microbial communication systems are widely spread in the bacterial realm and resemble those characteristic of eukaryotic multicellular organisms Microorganism engage in an ongoing dialogue with hpst cells and perform a plethora of functions in the composite superorganism. Literature data and the authors' own studies indicate the important role of catecholamines (biogenic amines), both in intra- and interspecific microbial communication and in the bidirectional microbiota-host dialog. The importance of this dialog for the maintenance of human health, psyche and social behavior, as well as the possibility of the creation of new drugs with targeted neurochemical effects, are discussed.



中文翻译:

儿茶酚胺与微生物、神经元和免疫细胞的相互作用

摘要

该综述介绍了二元宿主-微生物群系统中细胞通讯的最新数据。微生物通讯系统广泛分布在细菌领域,类似于真核多细胞生物的特征。微生物与 hpst 细胞进行持续对话,并在复合超生物中执行多种功能。文献数据和作者自己的研究表明儿茶酚胺(生物胺)在种内和种间微生物通讯以及双向微生物群与宿主对话中的重要作用。讨论了这种对话对于维持人类健康、心理和社会行为的重要性,以及开发具有靶向神经化学作用的新药的可能性。

更新日期:2021-08-19
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