Abstract: A 56-year-old man complaining of blurred vision was referred to the ophthalmologist. He was initially diagnosed with uveitis and showed no response to steroid treatment. Diagnostic vitrectomy and skin lesion biopsy performed later confirmed the diagnosis of extranodal NK/T cell lymphoma (ENKTL), nasal type. Despite sufficient systemic chemotherapy, the patient developed central nervous system (CNS) relapse 3 months after achieving systemic remission. The diagnosis and treatment of this patient required multidisciplinary teamwork between ophthalmologists, pathologists, and hematologists. This report focused on the diagnostic planning and optimal treatment strategy for this patient.

Keywords: extranodal NK/T-cell lymphoma, intraocular lymphoma, chemotherapy, central nervous system


中文翻译：

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结外 NK/T 细胞淋巴瘤主要发生在眼睛和中枢神经系统复发

摘要：一名 56 岁男性主诉视力模糊，被转诊至眼科医生处。他最初被诊断为葡萄膜炎，对类固醇治疗没有反应。后来进行的诊断性玻璃体切除术和皮肤病变活检证实了结外 NK/T 细胞淋巴瘤 (ENKTL)，鼻型的诊断。尽管进行了充分的全身化疗，但患者在达到全身缓解后 3 个月出现了中枢神经系统 (CNS) 复发。该患者的诊断和治疗需要眼科医生、病理学家和血液学家之间的多学科团队合作。本报告重点介绍了该患者的诊断计划和最佳治疗策略。

关键词：结外NK/T细胞淋巴瘤，眼内淋巴瘤，化疗，中枢神经系统