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Prostate cancer screening: a new way forward or another false start?
Nature Reviews Urology ( IF 15.3 ) Pub Date : 2021-08-19 , DOI: 10.1038/s41585-021-00513-w
Peter C Albertsen 1
Affiliation  

Serum PSA testing can identify men with clinically significant prostate cancer but exposes many more men to the diagnosis of indolent tumours. Benafif and colleagues have published the results of the BARCODE1 pilot study, in which they propose using germline single-nucleotide polymorphisms to identify men with a genetic risk of developing prostate cancer. Based on their preliminary findings, changing the current prostate cancer screening paradigm will be a challenge.

中文翻译:

前列腺癌筛查:新的前进方向还是另一个错误的开始?

血清 PSA 检测可以识别患有临床显着前列腺癌的男性,但会使更多男性面临惰性肿瘤的诊断。Benafif 及其同事发表了 BARCODE1 试点研究的结果,他们建议使用生殖系单核苷酸多态性来识别具有患前列腺癌遗传风险的男性。根据他们的初步发现,改变目前的前列腺癌筛查模式将是一项挑战。
更新日期:2021-08-19
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