Adipose tissue macrophages (ATMs) have important roles in the regulation of inflammatory responses and insulin resistance in obesity. A new study reports that a subpopulation of ATMs, TIM4+ resident ATMs, modulate adipocyte size via platelet-derived growth factor-CC production during development and diet-induced adipose tissue expansion.

中文翻译：

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TIM4+脂肪组织驻留巨噬细胞：肥胖的新调节剂

脂肪组织巨噬细胞 (ATM) 在调节肥胖症的炎症反应和胰岛素抵抗中具有重要作用。一项新的研究报告称，ATMs 的一个亚群，TIM4+ 常驻 ATMs，在发育和饮食诱导的脂肪组织扩张过程中通过血小板衍生生长因子-CC 的产生来调节脂肪细胞的大小。