A novel hydrogel was formed by mixing phenylboronic acid grafted sodium hyaluronate and polyvinyl alcohol based on the reversibility of the boronate ester bond. Moreover, a straightforward method has been exploited to directly prepare microneedle patches from a glucose-responsive hydrogel, which endows microneedle patches with good morphology and high drug loading capacity.

中文翻译：

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通过温和的胰岛素输送方法从水凝胶制备微针贴片

基于硼酸酯键的可逆性，将苯基硼酸接枝的透明质酸钠和聚乙烯醇混合形成了一种新型水凝胶。此外，已经开发了一种直接的方法从葡萄糖响应水凝胶直接制备微针贴片，这使微针贴片具有良好的形态和高载药量。