Implant-associated infections and aseptic loosening are some of the main reasons for implant failure. Therefore, there is an urgent need to improve the osseointegration and antibacterial capabilities of implant materials. In recent years, a large number of breakthroughs in the biological application of tantalum and its derivatives have been achieved. Owing to their corrosion resistance, biocompatibility, osseointegration ability, and antibacterial properties, they have shown considerable potential in orthopedic and dental implant applications. In this review, we provide the latest progress and achievements in the research on osseointegration and antibacterial properties of tantalum as well as its derivatives, and summarize the surface modification methods to enhance their osseointegration and antibacterial properties.

种植体相关感染和无菌性松动是种植体失败的一些主要原因。因此，迫切需要提高植入材料的骨整合和抗菌能力。近年来，钽及其衍生物在生物应用方面取得了大量突破。由于其耐腐蚀性、生物相容性、骨整合能力和抗菌性能，它们在骨科和牙科植入物应用中显示出相当大的潜力。在这篇综述中，我们提供了钽及其衍生物的骨结合和抗菌性能研究的最新进展和成果，并总结了提高其骨结合和抗菌性能的表面改性方法。