Background

Paragangliomas are rare neuroendocrine tumors, especially in the bladder. Although many paragangliomas are non-functional, functioning paragangliomas present with many non-specific signs and symptoms, such as hypertension and headache, complicating their diagnosis. Here, we report a case of micturition-induced severe headache associated with a bladder paraganglioma.

Case description: This report describes a severe headache disorder triggered by micturition and associated with a bladder paraganglioma in a middle-aged woman. Her pain occurred consistently after micturition, beginning from the left side of the nose and gradually extended to the forehead and the parietal and occipital regions. The headaches lasted 5–10 min. Removal of the paraganglioma completely eliminated the patient’s pain syndrome.

Conclusion

This case elucidates the association between micturition-triggered headaches and bladder paragangliomas. The presence of a post-micturition severe headache should suggest the possibility of a bladder paraganglioma.

中文翻译：

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与膀胱副神经节瘤相关的排尿引发的严重头痛：病例报告

背景

副神经节瘤是罕见的神经内分泌肿瘤，尤其是在膀胱中。尽管许多副神经节瘤是非功能性的，但功能性副神经节瘤存在许多非特异性体征和症状，例如高血压和头痛，使诊断复杂化。在这里，我们报告了一例与膀胱副神经节瘤相关的排尿引起的严重头痛。

病例描述：本报告描述了一种由排尿引发的严重头痛疾病，并与一名中年妇女的膀胱副神经节瘤有关。她的疼痛在排尿后持续出现，从鼻子左侧开始，逐渐延伸到前额、顶叶和枕骨区域。头痛持续了 5-10 分钟。切除副神经节瘤完全消除了患者的疼痛综合征。

结论

该病例阐明了排尿引发的头痛与膀胱副神经节瘤之间的关联。排尿后严重头痛的存在应提示膀胱副神经节瘤的可能性。