Abstract

Once it was believed that ribosomal RNA encodes proteins, and GTP hydrolysis supplies the energy for protein synthesis. Everything has changed, when Alexander Spirin joined the science. It turned out that proteins are encoded by a completely different RNA, and GTP hydrolysis only accelerates the process already provided with energy. It was Spirin who first put forward the idea of a Brownian ratchet and explained how and why molecular machines could arise in the RNA world.

中文翻译：

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Alexander Spirin 关于分子机器和生命起源

摘要

曾经认为核糖体 RNA 编码蛋白质，而 GTP 水解为蛋白质合成提供能量。当亚历山大·斯皮林加入科学界时，一切都变了。事实证明，蛋白质是由完全不同的 RNA 编码的，而 GTP 水解只会加速已经提供能量的过程。是斯匹林首先提出了布朗棘轮的想法，并解释了分子机器如何以及为什么会在 RNA 世界中出现。