Purpose of Review

Cardiac amyloidosis is an increasingly recognized condition with a growing range of targeted therapies, but diagnosis requires a high index of suspicion and multimodality imaging expertise. Early diagnosis remains key to improving quality of life and survival. This article reviews the multimodality imaging approach to the diagnosis, differentiation, and prognosis of cardiac amyloidosis.

Recent Findings

Recent advances in multimodality cardiac imaging have allowed for earlier diagnosis of cardiac amyloidosis resulting in earlier initiation of life-saving therapy in cases of light chain amyloidosis and life-prolonging therapy in transthyretin amyloidosis.

Summary

With these advances in multimodality imaging, it is important for cardiologists and cardiac imagers to be aware of the subtleties of early disease, the appropriate diagnostic approach as well as understanding the practicalities and pitfalls that are encountered with each modality.

中文翻译：

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心脏淀粉样变性的多模态成像

审查目的

心脏淀粉样变性是一种越来越被认可的疾病，靶向治疗的范围越来越广，但诊断需要高度怀疑和多模态成像专业知识。早期诊断仍然是提高生活质量和生存率的关键。本文综述了心脏淀粉样变性的诊断、鉴别和预后的多模态成像方法。

最近的发现

多模态心脏成像的最新进展允许对心脏淀粉样变性进行早期诊断，从而在轻链淀粉样变性病例中更早开始挽救生命的治疗，在甲状腺素运载蛋白淀粉样变性中进行延长生命的治疗。

概括

随着多模态成像的这些进步，心脏病专家和心脏成像师了解早期疾病的微妙之处、适当的诊断方法以及了解每种模式遇到的实用性和陷阱非常重要。