Purpose of Review

Chronic thromboembolic pulmonary hypertension (CTEPH), included in group 4 PH, is an uncommon complication of acute pulmonary embolism (PE), in which emboli in the pulmonary vasculature do not resolve but rather form into an organized scar-like obstruction which can result in right ventricular (RV) failure. Here we provide an overview of current diagnosis and management of CTEPH.

Recent Findings

CTEPH management is complex with treatments that range from surgery, percutaneous interventions, to medical therapies. Current CTEPH medical therapies have largely been repurposed from pulmonary arterial hypertension (PAH).

Summary

The diagnosis of CTEPH can be challenging, requiring a multimodality approach to differentiate from disease mimics. While these treatments improve symptoms, they may not reverse the underlying pathology of CTEPH.

中文翻译：

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慢性血栓栓塞性肺动脉高压：床边

审查目的

慢性血栓栓塞性肺动脉高压 (CTEPH) 属于第 4 组 PH，是急性肺栓塞 (PE) 的一种罕见并发症，其中肺血管系统中的栓子不会消退，而是形成有组织的疤痕样阻塞，可导致右心室 (RV) 衰竭。在这里，我们概述了 CTEPH 的当前诊断和管理。

最近的发现

CTEPH 管理复杂，治疗范围从手术、经皮介入治疗到药物治疗。目前的 CTEPH 医学疗法主要是从肺动脉高压 (PAH) 中改用而来。

概括

CTEPH 的诊断可能具有挑战性，需要采用多模式方法来区分疾病模拟物。虽然这些治疗可以改善症状，但它们可能无法逆转 CTEPH 的潜在病理。