Usually, the two-stage Masquelet induced-membrane technique for extremity reconstruction begins with a polymethylmethacrylate (PMMA) cement spacer-driven membrane, followed by an autologous cancellous bone graft implanted into the membrane cavity to promote healing of large bone defects. In exceptional cases, spacers made of polypropylene disposable syringes were successfully used instead of the usual PMMA spacers because of a PMMA cement shortage caused by a lack of resources. However, this approach lacks clinical evidence and requires experimental validation before being recommended as an alternative to the conventional technique.

中文翻译：

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Masquelet 技术：一次性聚丙烯注射器可以替代标准 PMMA 垫片吗？大鼠骨缺损模型。

通常，用于四肢重建的两阶段 Masquelet 诱导膜技术首先使用聚甲基丙烯酸甲酯 (PMMA) 水泥垫片驱动膜，然后将自体松质骨移植物植入膜腔中，以促进大骨缺损的愈合。在特殊情况下，由于资源缺乏导致 PMMA 水泥短缺，由聚丙烯一次性注射器制成的垫片成功地替代了通常的 PMMA 垫片。然而，这种方法缺乏临床证据，需要实验验证才能被推荐作为传统技术的替代方法。