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Ethical dimensions of translational developmental neuroscience research in autism
Journal of Child Psychology and Psychiatry ( IF 7.6 ) Pub Date : 2021-08-18 , DOI: 10.1111/jcpp.13494
Arianna Manzini 1, 2 , Emily J H Jones 3 , Tony Charman 4 , Mayada Elsabbagh 5, 6 , Mark H Johnson 3, 7 , Ilina Singh 8
Affiliation  

Since the 1990s, increasing research has been devoted to the identification of biomarkers for autism to help attain more objective diagnosis; enable early prediction of prognosis; and guide individualized intervention options. Early studies focused on the identification of genetic variants associated with autism, but more recently, research has expanded to investigate neurodevelopmental markers. While ethicists have extensively discussed issues around advances in autism genomics, much less ethical scrutiny has focused on research on early neurodevelopment and on the interventions being developed as a result.

中文翻译:

自闭症转化发展神经科学研究的伦理维度

自 1990 年代以来,越来越多的研究致力于鉴定自闭症的生物标志物,以帮助获得更客观的诊断;能够早期预测预后;并指导个性化的干预选择。早期研究侧重于识别与自闭症相关的遗传变异,但最近,研究已扩展到调查神经发育标记。虽然伦理学家广泛讨论了有关自闭症基因组学进展的问题,但很少有伦理审查关注早期神经发育研究和由此开发的干预措施。
更新日期:2021-08-18
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