Circular RNAs (circRNAs) are a novel type of non-coding RNA that plays major roles in the development of diverse diseases including osteonecrosis of the femoral head (ONFH). Here, we explored the impact of hsa_circ_0066523 derived from forkhead box P1 (FOXP1) (also called circFOXP1) on bone mesenchymal stem cells (BMSCs), which is important for ONFH development.

中文翻译：

---

Hsa_circ_0066523通过抑制PTEN促进骨间充质干细胞的增殖和成骨分化。

环状RNA（circRNA）是一种新型的非编码RNA，在包括股骨头坏死（ONFH）在内的多种疾病的发展中起重要作用。在这里，我们探讨了源自叉头盒 P1（FOXP1）（也称为 circFOXP1）的 hsa_circ_0066523 对骨间充质干细胞（BMSC）的影响，这对 ONFH 的发育很重要。