We aimed to investigate the characteristics and prognosis of high risk hospitalized patients identified by the rapid response system (RRS). A multicentered retrospective cohort study was conducted from June 2019 to December 2020. The National Early Warning Score (NEWS) was used for RRS activation. The outcome was unexpected intensive care unit (ICU) admission within 24 hours after RRS activation. The 11,459 patients with RRS activations were included. We found distinct clinical characteristics in patients who underwent ICU admission. All NEWS parameters were associated with the risk of unexpected ICU admission except body temperature. Body mass index, pulmonary disease, and cancer are related to the decreased risk of unexpected ICU admission. In conclusion, there were differences in clinical characteristics among high risk patients, and those differences were associated with unexpected ICU admissions. Clinicians should consider factors relating to unexpected ICU admission in the management of high risk patients identified by RRS.

中文翻译：

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快速反应系统确定的高恶化风险住院患者的特征和预后：一项多中心队列研究。

我们旨在调查由快速反应系统 (RRS) 确定的高危住院患者的特征和预后。一项多中心回顾性队列研究于 2019 年 6 月至 2020 年 12 月进行。国家早期预警评分 (NEWS) 用于 RRS 激活。结果是在 RRS 激活后 24 小时内意外入住重症监护病房 (ICU)。包括 11,459 名 RRS 激活患者。我们在入住 ICU 的患者中发现了不同的临床特征。除体温外，所有 NEWS 参数都与意外入住 ICU 的风险相关。体重指数、肺部疾病和癌症与意外入住 ICU 的风险降低有关。总之，高危患者的临床特征存在差异，这些差异与意外入住 ICU 相关。在管理 RRS 确定的高危患者时，临床医生应考虑与意外入住 ICU 相关的因素。