Abstract

Mn(II), Ni(II), Cu(II) complexes with the ionic liquid-supported Schiff base 1-{2-(2-hydroxy-5-chlorobenzylamine)ethyl}-3-methylimidazolium tetrafluoroborate (primary ligand) and 1-methyl imidazole (secondary ligand) and were synthesized and characterized by PXRD, SEM, ESI-MS, UV-Visible, FT-IR, ¹H NMR, ¹³CNMR spectroscopic and various analytical (elemental analysis and magnetic susceptibility measurements) methods. Based on these spectra and spectral data hexa coordinated geometries were assigned for the synthesized mixed ligand metal (II) complexes. Antimicrobial activity of the mixed ligand Mn(II), Ni(II), Cu(II) complexes with respect to the Schiff base against two gram positive (Staphylococcus aureus and Bacillus cereus) and two were gram negative (Escherichia coli and Klebsiella pneumoniae) were conducted to assess their antibacterial activities. The Schiff base along with the mixed ligand complexes exhibited very significant responses for gram positive and negative bacterial samples though maximum inhibition zone was produced by Ni(II) complex while the minimum inhibition zone was produced by Cu(II) complex in plates of Staphylococcus aureus.

摘要

Mn(II)、Ni(II)、Cu(II) 与离子液体负载的席夫碱 1-{2-(2-羟基-5-氯苄胺)乙基}-3-甲基咪唑鎓四氟硼酸盐（主要配体）和 1 -甲基咪唑（二级配体）并通过PXRD，SEM，ESI-MS，UV-Visible，FT-IR，¹ H NMR，¹³ CNMR光谱和各种分析（元素分析和磁化率测量）方法进行合成和表征。基于这些光谱和光谱数据，为合成的混合配体金属 (II) 配合物分配了六配位几何结构。混合配体 Mn(II)、Ni(II)、Cu(II) 配合物相对于席夫碱对两种革兰氏阳性（金黄色葡萄球菌和蜡状芽孢杆菌）的抗菌活性）和两个革兰氏阴性菌（大肠杆菌和肺炎克雷伯菌）进行了评估它们的抗菌活性。席夫碱和混合配体复合物对革兰氏阳性和阴性细菌样品表现出非常显着的反应，尽管在金黄色葡萄球菌平板中，Ni(II) 复合物产生最大抑菌圈，而 Cu(II) 复合物产生最小抑菌圈.