Continuous flow chemistry is becoming an established technology platform that finds frequent application in industrial chemical manufacture with support and endorsements by the FDA for pharmaceuticals. Amongst the various advantages that are commonly cited for flow chemistry over batch processing, sustainability continues to require further advances and joint efforts by chemists and chemical engineers in both academia and industry. This short review highlights developments between 2015 and early 2021 that positively impact on the green credentials associated with flow chemistry, specifically when applied to the preparation of pharmaceuticals. An industrial perspective on current challenges is provided to whet discussion and stimulate further investment towards achieving greener modern synthetic technologies.1 Introduction2 Subject Areas and Relevant Case Studies3 Industrial Outlook on Future Sustainability Driven through Continuous Manufacturing Approaches4 Conclusions and Outlook

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评估流动化学对工业应用的绿色认证

连续流动化学正在成为一个成熟的技术平台，在 FDA 的制药支持和认可下，它在工业化学品制造中得到了频繁的应用。在流动化学优于批处理的各种优势中，可持续性继续需要学术界和工业界的化学家和化学工程师的进一步进步和共同努力。这篇简短的评论重点介绍了 2015 年至 2021 年初的发展，这些发展对与流动化学相关的绿色证书产生了积极影响，特别是在应用于药物制备时。提供了对当前挑战的工业观点，以激发讨论并刺激进一步投资以实现更绿色的现代合成技术。