α,β-Unsaturated δ-lactones are structural motifs found in diverse pharmacologically active natural products. In fact, the unsaturated lactone is often responsible for the biological activity. Herein, we report a new approach for the syntheses of (R)-argentilactone and (R)-goniothalamin based on a photoredox intermolecular iodolactonization mediated by a photoredox process. This new approach, already employed in our research group, stands as a new methodology to achieve several natural products containing α,β-unsaturated δ-lactones.

中文翻译：

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(R)-Argentilactone 和 (R)-Goniothalamin 使用自由基光氧化还原方法合成 α,β-不饱和 δ-内酯

α,β-不饱和 δ-内酯是在多种药理活性天然产物中发现的结构基序。事实上，不饱和内酯通常负责生物活性。在此，我们报告了一种基于光氧化还原过程介导的光氧化还原分子间碘内酯化合成 (R)-argentilactone 和 (R)-goniothalamin 的新方法。这种新方法已经在我们的研究小组中使用，是一种新方法，可以实现多种含有 α,β-不饱和 δ-内酯的天然产物。