The antimicrobial bioactivity of silver nanoparticles is well known, and they can be used widely in many applications, becoming especially important in the biomedical industry. On the other hand, the electrospun nanofibers possess properties that can enhance silver nanoparticle applicability. However, silver nanoparticle bioactivity differs depending on the loading of silver ions into electrospun nanofibers. This review is aimed at comparing different silver incorporation methods into electrospun nanofibers and their antimicrobial activity, discussing each procedure’s limitations, and presenting the most promising one. This review showed that the preferred techniques for incorporating silver nanoparticles were direct blending and ultraviolet irradiation methods due to their simplicity and efficient results. Besides, polyacrylonitrile nanofibers (PAN) have been the most reported system loaded with silver nanoparticles. Finally, independently of the technique used, silver nanoparticle-loaded nanofibers show high antimicrobial activity in all cases.

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载有银纳米粒子的静电纺纳米纤维的抗菌作用：银掺入方法的影响

银纳米粒子的抗菌生物活性是众所周知的，它们可以广泛用于许多应用，在生物医学工业中变得尤为重要。另一方面，电纺纳米纤维具有可以增强银纳米颗粒适用性的特性。然而，银纳米颗粒的生物活性因银离子在电纺纳米纤维中的负载而异。本综述旨在比较不同的银掺入电纺纳米纤维的方法及其抗菌活性，讨论每种方法的局限性，并提出最有希望的方法。该综述表明，掺入银纳米粒子的首选技术是直接混合和紫外线照射方法由于其简单和有效的结果。此外，聚丙烯腈纳米纤维（PAN）是报道最多的载有银纳米粒子的系统。最后，独立于所使用的技术，载有银纳米颗粒的纳米纤维在所有情况下都显示出高抗菌活性。