The catalytic dicarbofunctionalization of unsaturated π bonds represents a powerful platform for the rapid construction of complex motifs. Despite remarkable progress, novel and efficient methods for achieving such transformations under milder conditions with chemo-, regio-, and stereoselectivity still remain a significant challenge; thus, their development is highly desirable. Recently, the merging of nickel catalysis with radical chemistry offers a new and benign platform for the catalytic dicarbofunctionalization of unsaturated π bonds with unprecedented reactivity and selectivity. In this review, we summarize the recent advances in this area by underpinning the catalytic domino transformations involving radical capture by nickel to provide a clear overview of reaction designs and mechanistic scenarios.

中文翻译：

---

涉及镍自由基捕获的催化三组分双碳官能化反应

不饱和 π 键的催化双碳功能化代表了快速构建复杂基序的强大平台。尽管取得了显着进展，但在温和条件下实现具有化学选择性、区域选择性和立体选择性的这种转化的新方法和有效方法仍然是一个重大挑战。因此，它们的发展是非常可取的。最近，镍催化与自由基化学的结合为不饱和 π 键的催化双碳官能化提供了一个新的良性平台，具有前所未有的反应性和选择性。在这篇综述中，我们通过支持涉及镍自由基捕获的催化多米诺转化来总结该领域的最新进展，以提供对反应设计和机制场景的清晰概述。