Homochiral helical self-organizations provide some of the most fundamental architectures of biological macromolecules and of their co-assemblies although they were first discovered and elucidated only during the early 1950. Helical synthetic covalent macromolecules started to be discovered soon after and were followed by supramolecular macromolecules and their co-assemblies few decades later. This perspective will provide a brief historical development of chiral helical self-organizations in biology and in supramolecular chemistry. Helical covalent and supramolecular macromolecules self-organize and co-organize helical supramolecular columns and spherical helices that can generate complex liquid crystals, crystals including Frank-Kasper phases, and quasicrystals. The design of new functions based on synthetic helical assemblies will also be discussed. Personal events from the life of scientists contributing to these developments are also briefly mentioned.

中文翻译：

---

超分子柱和球体的螺旋手性自组织复杂液晶、晶体和准晶体

同手性螺旋自组织提供了生物大分子及其共组装体的一些最基本的结构，尽管它们仅在 1950 年初才首次被发现和阐明。 螺旋合成共价大分子在不久之后开始被发现，随后是超分子大分子以及他们几十年后的共同组装。这一观点将提供生物学和超分子化学中手性螺旋自组织的简要历史发展。螺旋共价和超分子大分子自组织和共组织螺旋超分子柱和球形螺旋，可以产生复杂的液晶、包括 Frank-Kasper 相在内的晶体和准晶体。还将讨论基于合成螺旋组件的新功能设计。还简要提及了对这些发展做出贡献的科学家生活中的个人事件。