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Towards optimizing peptide-based inhibitors of protein–protein interactions: predictive saturation variation scanning (PreSaVS)
RSC Chemical Biology Pub Date : 2021-08-16 , DOI: 10.1039/d1cb00137j
Kristina Hetherington 1, 2 , Som Dutt 1, 2 , Amaurys A Ibarra 3 , Emma E Cawood 1, 2 , Fruzsina Hobor 1, 4 , Derek N Woolfson 3, 5, 6 , Thomas A Edwards 1, 4 , Adam Nelson 1, 2 , Richard B Sessions 3, 6 , Andrew J Wilson 1, 2
Affiliation  

A simple-to-implement and experimentally validated computational workflow for sequence modification of peptide inhibitors of protein–protein interactions (PPIs) is described.

中文翻译:

优化蛋白质-蛋白质相互作用的基于肽的抑制剂:预测饱和度变化扫描(PreSaVS)

描述了一种易于实施且经过实验验证的计算工作流程,用于对蛋白质-蛋白质相互作用 (PPI) 的肽抑制剂进行序列修饰。
更新日期:2021-08-16
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