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In vitro and in silico modeling of endovascular stroke treatments for acute ischemic stroke
Journal of Biomechanics ( IF 2.4 ) Pub Date : 2021-08-14 , DOI: 10.1016/j.jbiomech.2021.110693
Giulia Luraghi 1 , Rachel M E Cahalane 2 , Emma van de Ven 3 , Serena C M Overschie 3 , Frank J H Gijsen 4 , Ali C Akyildiz 4
Affiliation  

Acute ischemic stroke occurs when a thrombus obstructs a cerebral artery, leading to sub-optimal blood perfusion to brain tissue. A recently developed, preventive treatment is the endovascular stroke treatment (EVT), which is a minimally invasive procedure, involving the use of stent-retrievers and/or aspiration catheters. Despite its increasing use, many critical factors of EVT are not well understood. In this respect, in vitro, and in silico studies have the great potential to help us deepen our understanding of the procedure, perform further device and procedural optimization, and help in clinical training. This review paper provides an overview of the previous in vitro and in silico evaluations of EVT treatments, with a special emphasis on the four main aspects of the adopted experimental and numerical set-ups: vessel, thrombus, device, and procedural settings.



中文翻译:

急性缺血性卒中血管内卒中治疗的体外和计算机模拟

当血栓阻塞脑动脉时会发生急性缺血性中风,导致脑组织的血液灌注不足。最近开发的预防性治疗是血管内中风治疗 (EVT),这是一种微创手术,涉及使用支架回收器和/或抽吸导管。尽管 EVT 的使用越来越多,但 EVT 的许多关键因素还没有得到很好的理解。在这方面,体外和计算机研究具有巨大的潜力,可以帮助我们加深对程序的理解,进行进一步的设备和程序优化,并有助于临床培训。这篇综述论文概述了先前对 EVT 治疗的体外和计算机评估,特别强调了所采用的实验和数值设置的四个主要方面:血管、血栓、装置、

更新日期:2021-08-24
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