Normocalcemic primary hyperparathyroidism is an entity on which several issues about its clinical management remains unclear. This is reflected in the main current guidelines, where there are no evidence-based specific recommendations. Through an exhaustive review of current literature, a clinical management algorithm for these patients is proposed. We consider the diagnosis criteria, the differential diagnosis, the clinical manifestations, and the treatment indications. When indicated, we also review the preoperative locations techniques and the surgical approach. Finally, when surgical treatment is not indicated, the patient is not a candidate to surgery or refuse surgical management, we review the medical treatment options and the follow-up schemes.

血钙正常的原发性甲状旁腺功能亢进症是一个关于其临床管理的几个问题仍不清楚的实体。这反映在当前的主要指南中，其中没有基于证据的具体建议。通过对当前文献的详尽回顾，提出了针对这些患者的临床管理算法。我们考虑诊断标准、鉴别诊断、临床表现和治疗指征。当需要时，我们还会回顾术前定位技术和手术方法。最后，当没有手术治疗指征，患者不适合手术或拒绝手术治疗时，我们会审查医疗方案和随访方案。