In reflecting the author's personal perspective, this review demonstrates how chirality is a unifying theme in modern science. Using the discrete symmetries of parity P, time reversal T and charge conjugation C to characterize chiral systems, the concepts of true and false chirality that emerge provide an extension of Lord Kelvin's definition to dynamic situations This clarifies the nature of physical influences able to induce absolute enantioselection, emphasizing the distinct behaviour of processes under thermodynamic and kinetic control. Parity violation and CP violation are suggested to be manifestations of true and false cosmic chirality, respectively, with possible roles in abiotic enantioselection. Truly chiral systems support time-even pseudoscalar observables which endows chiroptical spectroscopies with a special sensitivity to absolute stereochemistry, exemplified by the application of vibrational Raman optical activity to small chiral organic molecules and intact viruses.

中文翻译：

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对称性和手性：物理学与化学和生物学握手的地方

在反映作者的个人观点时，这篇评论展示了手性如何成为现代科学中的一个统一主题。使用奇偶性P的离散对称性、时间反转T和电荷共轭C来表征手性系统，出现的真假手性概念将开尔文勋爵的定义扩展到动态情况这阐明了能够引起绝对的物理影响的性质对映选择，强调在热力学和动力学控制下过程的独特行为。奇偶违例和CP违反分别是真和假宇宙手性的表现，可能在非生物对映选择中起作用。真正的手性系统支持时间偶数伪标量观测，这使手性光谱对绝对立体化学具有特殊敏感性，例如将振动拉曼光学活性应用于小手性有机分子和完整病毒。