Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiological syndrome often associated with immunosuppressant drug use, renal disease, and eclampsia and characterized by parieto-occipital vasogenic edema that usually resolves within days. Globally and in the settings of renal transplant, literature concerning PRES is very scattered. In this report, we provide two cases, one diagnosed with IgA nephropathy and another with nephrotic syndrome type 9 that developed episodes of tonic-clonic seizure immediately after renal transplant in case 1 and four days post-transplant in case 2. The two patients had a history of hypertension, renal disease, corticosteroid and immunosuppressant drug use. Neuro-imaging showed typical vasogenic edema involving the parieto-occipital areas. Therefore, the clinical-radiological presentation confirmed the diagnosis of PRES in both cases. Also, rapid neurologic recovery was witnessed upon administration of anti-epileptic and anti-hypertensive medications. Non-discontinuation of immunosuppressants, steroids, early symptomatic management, and blood pressure control are favorable factors that might explain the rapid recovery of these two patients.

后部可逆性脑病综合征 (PRES) 是一种临床放射学综合征，通常与使用免疫抑制剂、肾脏疾病和子痫有关，其特征是通常在数天内消退的顶枕血管源性水肿。在全球范围内以及在肾移植领域，有关 PRES 的文献非常分散。在本报告中，我们提供了两个病例，一个被诊断为 IgA 肾病，另一个被诊断为 9 型肾病综合征，在病例 1 和移植后 4 天出现强直-阵挛性癫痫发作的病例 1 和病例 2。这两名患者有有高血压、肾病、皮质类固醇和免疫抑制剂药物使用史。神经影像显示典型的血管源性水肿累及顶枕区。所以，临床放射学表现证实了这两个病例的 PRES 诊断。此外，在服用抗癫痫和抗高血压药物后，神经功能迅速恢复。未停用免疫抑制剂、类固醇、早期症状管理和血压控制是可能解释这两名患者快速康复的有利因素。