Epigenetics play an essential role in the occurrence and improvement of many diseases. Evidence shows that epigenetic modifications are crucial to the regulation of gene expression. DNA methylation is closely linked to embryonic development in mammalian. In recent years, epigenetic drugs have shown unexpected therapeutic effects on neurological diseases, leading to the study of the epigenetic mechanism in neurodegenerative diseases. Unlike genetics, epigenetics modify the genome without changing the DNA sequence. Research shows that epigenetics is involved in all aspects of neurodegenerative diseases. The study of epigenetic will provide valuable insights into the molecular mechanism of neurodegenerative diseases, which may lead to new treatments and diagnoses. This article reviews the role of epigenetic modifications neurodegenerative diseases with dyskinesia, and discusses the therapeutic potential of epigenetic drugs in neurodegenerative diseases.

表观遗传学在许多疾病的发生和改善中起着至关重要的作用。有证据表明，表观遗传修饰对基因表达的调节至关重要。DNA甲基化与哺乳动物的胚胎发育密切相关。近年来，表观遗传药物对神经系统疾病表现出意想不到的治疗效果，引发了对神经退行性疾病表观遗传机制的研究。与遗传学不同，表观遗传学在不改变 DNA 序列的情况下修改基因组。研究表明，表观遗传学涉及神经退行性疾病的各个方面。表观遗传学的研究将为神经退行性疾病的分子机制提供有价值的见解，这可能会导致新的治疗和诊断。