Many biomedical applications, titanium dioxide (TiO₂) nanoparticles are used. They have been used for drugs delivery and targeting, skin tone protection, reinforcement materials etc. It is biocompatible and non-toxic in nature. The healing of wounds are delayed mainly due to infections. Infections make the process of wound healing complex. Nanomaterials are used for enhancing wound healing mainly due to their ability to inhibit bacterial growth. Nanoparticles of TiO₂ are synthesized using a chemical method. They are annealed at different temperature to increase the particle size. XRD (X-ray diffraction), FTIR (Fourier Transform infrared spectroscopy), and TEM (Transmission electron Microscopy) are used to classify the samples. The influence of particle size and phase transformation on fibroblast cell proliferation. F-actin, cell movement are analysed. It is found that the antimicrobial activity increases with decrease in particle size. This study confirms the utilization of TiO₂ nanoparticles for wound healing applications.

许多生物医学应用都使用二氧化钛 (TiO ₂ ) 纳米颗粒。它们已被用于药物递送和靶向、肤色保护、增强材料等。它具有生物相容性和无毒性质。伤口愈合延迟主要是由于感染。感染使伤口愈合过程变得复杂。纳米材料用于促进伤口愈合主要是因为它们具有抑制细菌生长的能力。TiO ₂纳米粒子是用化学方法合成的。它们在不同温度下退火以增加粒度。XRD（X 射线衍射）、FTIR（傅立叶变换红外光谱）和 TEM（透射电子显微镜）用于对样品进行分类。粒径和相变对成纤维细胞增殖的影响。分析 F-肌动蛋白、细胞运动。发现抗微生物活性随着粒径的减小而增加。该研究证实了 TiO ₂纳米颗粒在伤口愈合应用中的应用。