The “Alice in Wonderland syndrome” (AIWS) is a neurological disorder characterized by altered body schema perception, visual, or somesthetic symptoms, which is frequently associated with migraine. In this article, we present the earliest known description of symptoms attributable to AIWS in the medical literature. During a lecture held on November 22, 1887, at the Salpêtrière, Jean-Martin Charcot (1825–1893) examined a patient with somesthetic symptoms (partial macrosomatognosia) in the context of migraine with aura. Although this condition was not known at the time, Charcot tried to provide an accurate semiological and nosographic framework of this case, attributing the complex of symptoms to migraine with aura and epilepsy with sensory symptoms. With intellectual honesty and clinical prudence, Charcot correctly pointed to a disturbance in the excitability of cortical areas responsible for processing and perceiving sensory stimuli.

“爱丽丝梦游仙境综合征”（AIWS）是一种以身体图式感知、视觉或躯体感觉症状改变为特征的神经系统疾病，通常与偏头痛相关。在本文中，我们介绍了医学文献中已知最早的 AIWS 症状描述。在 1887 年 11 月 22 日在 Salpêtrière 举行的一次演讲中，让-马丁·夏科 (Jean-Martin Charcot)（1825-1893 年）在先兆偏头痛的背景下检查了一名有躯体感觉症状（部分巨体认认症）的患者。尽管当时这种情况并不为人所知，但夏科特试图为该病例提供准确的符号学和病史框架，将症状的复杂性归因于先兆偏头痛和伴有感觉症状的癫痫。凭着理智的诚实和临床上的审慎，