The main aim of this work was to develop a magnetic molecularly imprinted polymer (MMIP)-based quantum dots electrochemiluminescent (ECL) probe for the ultrasensitive and highly selective detection of bisphenol A (BPA). The prepared core-shell Fe₃O₄@SiO₂ exhibited superparamagnetic properties, making them easy to separate. The MIP was fabricated by the self-polymerization of dopamine on the surface of amine-terminated Fe₃O₄@SiO₂ (Fe₃O₄@SiO₂-NH₂) magnetic nanoparticles and doped with quantum dots (QDs) to form an ECL system. The ECL intensity decrease with the concentration of BPA increased, due to the BPA molecules occupied molecularly imprinted sites and blocked the strong ECL emission of QDs. The prepared ECL sensor performed satisfactorily in the detection of BPA, with a wide linear range from 10^− 4 to 10^− 9 mol L^− 1 and a low detection limit of 3.4 × 10^− 10 mol L^− 1 (S/N = 3). The recoveries of BPA achieved were in the range 96%–107% in the detection of actual water samples. The proposed ECL sensor displayed high sensitivity and stability, and may provide an approach for determining other important analytes.

这项工作的主要目的是开发一种基于磁性分子印迹聚合物 (MMIP) 的量子点电化学发光 (ECL) 探针，用于双酚 A (BPA) 的超灵敏和高选择性检测。制备的核壳 Fe ₃ O ₄ @SiO ₂表现出超顺磁性，使其易于分离。MIP是通过多巴胺在胺封端的Fe ₃ O ₄ @SiO ₂ (Fe ₃ O ₄ @SiO ₂ -NH ₂) 磁性纳米粒子并掺杂量子点 (QD) 以形成 ECL 系统。ECL 强度随着 BPA 浓度的增加而降低，这是由于 BPA 分子占据了分子印迹位点并阻挡了 QD 的强 ECL 发射。制备的 ECL 传感器在 BPA 的检测中表现令人满意，线性范围从 10 ^{- 4}到 10 ^{- 9}  mol L ^{- 1}和低检测限为 3.4 × 10 ^{- 10}  mol L ^{- 1} (S/N = 3 ）。在实际水样的检测中，BPA 的回收率在 96%–107% 范围内。所提出的 ECL 传感器显示出高灵敏度和稳定性，并可能为确定其他重要分析物提供一种方法。